Grant Holder |
Researcher |
Completed project Institute Amount Awarded Duration Type of Award |
Title
Characterisation of Scottish founder mutations in BRCA1 and BRCA 1
Synopsis
Family history is the strongest recognised risk for breast cancer, and screening for ‘founder’ mutations is technically straightforward once they have been characterised. This study will help to identify young women at high genetic risk and so target resources more efficiently to those at greatest need.
Aims & Goals
By studying genetic risk factors for breast cancer that are found particularly in the Scottish population, we can ask how they interact with diet and other ‘lifestyle’ risk factors. This will help families at high risk to protect themselves from the disease but will also shed light on the fundamental causes of breast cancer.
Publications
| Title | Survival in prospectively ascertained familial breast cancer: analysis of a series stratified by tumour characteristics, BRCA muatations and oophorectomy. |
| Year | 2002 |
| Authors | Moller P, Borg A, Evans DGR, Haites N, Reis M, Vasen H, Anderson E, Steel CM, et al. |
| Title | The Scottish/Northern Irish BRCA1/BRCA2 Consortium. BRCA1 and BRCA2 mutations in Scotland and Northern Ireland. |
| Year | 2003 |
| Authors | E Anderson, V Anderson, D Baty, C Beers, C Bell, D Black, R Black, M Boyd, A Bradley, D Brewster, I Brown, J Campbell, R Cetnarskyj, B Cohen, S Cooke, R Davidson, F Douglas, S Drummond, A Fordyce, B Gibbons, D Goudie, C Graham, H Gregory, N Haites, W John |
