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Grant Holder Dr Nicholas D Lakin

Current project Oxford - London & South East England Institute University of Oxford Amount Awarded £14,570.00 Duration 12 months Type of Award Small Pilot Grant

Title

Regulation of BRCA2 in response to DNA damage

Synopsis

Having a mutated form of the BRCA2 gene leads to an 85 percent lifetime risk of developing breast cancer. Dr Lakin believes that the BRCA2 gene works to protect other genes in the body from becoming mutated by ensuring that mistakes are not made if their DNA has to be repaired

Aims & Goals

The aim of this research is to look at how BRCA2 works and try to identify other genes that may contribute to an increased risk of breast cancer when they become mutated This research will lead to a better understanding of how breast cancer develops and may provide to determine a persons likelihood of developing breast cancer.

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