Grant Holder
Dr Paul Edwards

Researcher
Dr Yii Leng Chua

Completed project
Cambridge - Anglia

Institute
University of Cambridge

Amount Awarded
£144,301.00

Duration
36 months

Type of Award
Project grant

Title

Chromosome translocations that target NRG1/heregulin in breast cancers

Synopsis

Dr Edwards is looking at what happens when chromosomes (bundles of genes) are broken and incorrectly rejoin to form new �fusion genes� to see if they play any part in breast cancer development.

Publications

Title A recurrent chromosome breakpoint in breast cancer at the NRG1/neuregulin 1/heregulin gene.
Year 2005
Authors Huai-En Huang, Suet-Feung Chin, Christophe Ginestier, Valérie-Jeanne Bardou, José Adélaïde, N. Gopalakrishna Iyer, Maria J. Garcia, Jessica C. Pole, Grace M. Callagy, Stephen M. Hewitt, William J. Gullick, Jocelyne Jacquemier, Carlos Caldas, Max Chaffanet

Presentations

Title Chromosome aberrations, the heregulin gene NRG1 and breast cancer
Year 2004
Authors Chua YL, Huang HE, Pole JCM and Edwards PAW

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