Grant Holder |
Researcher |
Completed project Institute Amount Awarded Duration Type of Award |
Title
The role of cyclin-dependent kinase inhibitors in human breast cell differentiation
Synopsis
The risk of breast cancer is related partly to the balance between cell exposure to factors which promote cancer cell growth, such as oestrogen, and those which encourage cell specialisation, such as an early full term pregnancy, which protect against breast cancer. This project aims to discover where such specialisations come from, what controls them and whether the number of such cells correlates with breast cancer risk.
Aims & Goals
With this generous funding from the Breast Cancer Campaign, we can use state of the art techniques to help us find more about how normal breast cells become cancer cells. These studies may also provide new ways of predicting a woman’s risk of developing breast cancer.
Presentations
| Title | Interaction of cyclin dependent kinase inhibitors and extracellular matrix in regulation of breast epithelial cell differentiation and acinar morphogenesis |
| Year | 2003 |
| Authors | HA Coppock, RB Clarke |
